We lead busy lives in a very fast-paced world, and sometimes it is difficult to keep up. Even when we try to avoid the hustle and bustle, we can often find ourselves feeling stressed, anxious, overwhelmed, frantic, rushed, or any number of feelings that wear and tear on the mind and body until fatigue and exhaustion finally take over.
When we continually live in such high stress environments, it actually changes the chemistry of the body. In times of stress, the body goes into a “fight or flight” response to deal with the stress of the moment, similar to an animal trying to escape a predator. When your body is in this fight or flight state, it prioritizes the energy use towards short-term survival goals to get it through the immediate threat.
The body does not want to waste energy on repairing and maintaining itself when there are immediate stresses that need to be dealt with. This means that during prolonged periods of stress the immune system does not work as well, wounds do not heal as fast, cells stop repairing themselves and replicating, and free-radicals build up causing cellular damage and inflammation. It’s easy to see how a person can start feeling run-down and out of energy after even short periods of stress.
In order to combat these effects, it is important to know how the cells in your body get the energy they need to thrive. Energy is produced in the cell by tiny “engines” called mitochondria. This is the place where calories from your diet react with oxygen to create energy in a form that the cell can use. The more energy a cell requires, the more mitochondria are present in that cell. Most cells contain a couple hundred mitochondria, but in the organs that require the most energy like the liver, heart, and brain there are thousands of mitochondria in every cell! When energy is being diverted to other systems to deal with stress, these high-energy organs are the ones that stand to suffer the most.
Many of the body’s systems suffer during prolonged periods of stress, but we usually first begin to notice the effects in our brains. We often experience this after a long day of work or studying – or even just keeping up with our daily activities – our minds become fatigued and it becomes difficult to concentrate and stay alert. We feel a “brain-fog” that makes it difficult to think and eventually we know our mind just needs a break. The problem is that just because our brains are ready for some rest does not mean that we are able to give it the rest it needs. The day is only halfway done, but all our brains want to do is rest.
This is generally the point when people search for something to help perk them up. Unfortunately, the first things people seek usually contain a combination of mega-doses of caffeine and an unhealthy amount of sugar or artificial sweeteners. Sometimes doctors even prescribe amphetamine-based medications to help people get through their days.
These methods might provide some feelings of improved energy, but they do not address some of the underlying biochemistry behind the fatigue – that is, they do not address the “fight or flight” stress response that your body is experiencing, or the damage that is occurring on a cellular level. Even worse, some of the energy products on the market can contain potentially dangerous amounts of certain ingredients, especially when more than one serving size is consumed at a time.
Viniferamine Energy Support was developed with all of this in mind to ensure absolute safety and efficacy. It begins with the patented and scientifically tested Olivamine 10 Max that protects you from the negative effects of stress and fatigue on a cellular level. It helps protect the mitochondria from free-radical damage by actually turning on natural repair mechanisms within the mitochondria and allowing them to continue efficiently producing energy for the cell.
Meanwhile, ingredients like Green Tea, L-taurine, and Rhodiola Rosea work to counterbalance the effects of stress and fatigue. The green tea extract also provides a small amount of caffeine, equivalent to about one cup of drip coffee, to help with feelings of alertness. All of these ingredients combine to naturally restore energy, allowing you to stay focused with mental clarity through the entire day.
What does the research say about the ingredients in Viniferamine Energy Support?
Olivamine 10 contains ingredients that are known to be vital to the health of the cell and the energy-producing mitochondria found inside. The precise balance of the ingredients found in Olivamine 10 Max including hydroxytyrosol from the olive and N-acetyl-L-cysteine have been shown to turn on specific genes involved in protecting mitochondria and DNA from free radical damage including two extremely potent antioxidants, MnSOD and glutathione.1–8
Green Tea is known to possess many health benefits, largely because of the content of antioxidants such as ECG and EGCG. Studies on the long-term administration of green tea catechins have demonstrated improved learning ability, memory, and physical endurance. Green Tea extract naturally contains caffeine, and contributes the equivalent of about one cup of drip coffee worth of caffeine in 2 capsules of Pinnaclife Energy Support. Caffeine has been shown to improve alertness and attention and is commonly used for this purpose.9-14
L-Taurine is a sulfur-containing amino acid produced naturally in the body and it is found in high concentrations in the brain and muscles. Research has indicated that supplementing with taurine may help to improve learning and retention, and reduce age-dependent decline in spatial memory acquisition and retention. Taurine has also been shown to help improve athletic performance and endurance.15–21
Rhodiola Rosea is a plant found in alpine regions, especially in Northern Asia. The plant has been used for centuries for a variety of ailments and is included in official Russian medicine for use as a stimulant for fatigue, psychiatric and neurological conditions, and in healthy individuals to relieve fatigue, increase attention span, memory, and work productivity. Sweden recognizes Rhodiola Rosea as an Herbal Medicinal Product, describing it in the Textbook of Phytomedicine for Pharmacists as an anti-fatigue agent with stimulant action. The biological activity is thought to come primarily from a compound called rosavin. Several double-blind placebo controlled trials have been conducted in humans with significant results indicating improvements in mental performance, psychomotor function, mental fatigue, stress-induced fatigue, irritability, distractibility, weakness, work productivity and feelings of well being.22–30
- Sarsour EH, Kumar MG, Kalen AL, Goswami M, Buettner GR, Goswami PC. MnSOD activity regulates hydroxytyrosol-induced extension of chronological lifespan. Age. 2011;34:95–109.
- Sarsour EH, Kumar MG, Chaudhuri L, Kalen AL, Goswami PC. Redox control of the cell cycle in health and disease. Antioxid Redox Signal. 2009;11(12):2985–3011.
- Sarsour EH, Kalen AL, Xiao Z, et al. Manganese superoxide dismutase regulates a metabolic switch during the mammalian cell cycle. Cancer Res. 2012;E.Pub:1–24. Available at: http://www.ncbi.nlm.nih.gov/pubmed/22710435
- Sarsour EH, Venkataraman S, Kalen AL, Oberley LW, Goswami PC. Manganese superoxide dismutase activity regulates transitions between quiescent and proliferative growth. Aging Cell. 2008;7:405–17.
- Zhang F, Lau SS, Monks TJ. The Cytoprotective Effect of N-acetyl- L -cysteine against ROS-Induced Cytotoxicity Is Independent of Its Ability to Enhance Glutathione Synthesis. 2011;120(1):87–97
- Atkuri KR, Mantovani JJ, Herzenberg L a, Herzenberg L a. N-Acetylcysteine–a safe antidote for cysteine/glutathione deficiency. Curr Opin Pharmacol. 2007;7(4):355–9.
- Kelly GS. Clinical applications of N-acetylcysteine. Altern Med Rev. 1998;3(2):114–27. Available at: http://www.ncbi.nlm.nih.gov/pubmed/9577247.
- González-Correa JA, Navas MD, Lopez-Villodres JA, Trujillo M, Espartero JL, De La Cruz JP. Neuroprotective effect of hydroxytyrosol and hydroxytyrosol acetate in rat brain slices subjected to hypoxia-reoxygenation. Neurosci Lett. 2008;446(2-3):143–6.
- Haque AM, Hashimoto M, Katakura M, Tanabe Y, Hara Y, Shido O. Ingestive Behavior and Neurosciences Long-Term Administration of Green Tea Catechins Improves Spatial Cognition Learning Ability in Rats 1. Ingestive Behav Neurosci. 2006;136:1043–1047.
- Brunyé TT, Mahoney CR, Lieberman HR, Taylor H a. Caffeine modulates attention network function. Brain Cogn. 2010;72(2):181–8.
- Sun AY, Wang Q, Simonyi A, Sun GY. Botanical phenolics and brain health. Neuromolecular Med. 2008;10(4):259–74.
- Zhu W-L, Shi H-S, Wei Y-M, et al. Green tea polyphenols produce antidepressant-like effects in adult mice. Pharmacol Res. 2012;65(1):74–80.
- Murase T, Haramizu S, Shimotoyodome A, Tokimitsu I, Hase T. Green tea extract improves running endurance in mice by stimulating lipid utilization during exercise. Am J Physiol Regul Integr Comp Physiol. 2006;290(6):R1550–6.
- Chung JH, Han JH, Hwang EJ, et al. Dual mechanisms of green tea extract (EGCG)-induced cell survival in human epidermal keratinocytes. FASEB J. 2003;17(13):1913–5.
- El Idrissi A. Taurine improves learning and retention in aged mice. Neurosci Lett. 2008;436(1):19–22.
- El Idrissi A, Shen CH, L’amoreaux WJ. Neuroprotective role of taurine during aging. Amino Acids. 2013;45(4):735–50.
- Kumari N, Prentice H, Wu J. Taurine and Its Neuroprotective Role. In: El Idrissi A, L’Amoreaux WJ, eds. Taurine 8 (Advances in Experimental Medicine and Biology).Vol 775. Advances in Experimental Medicine and Biology. New York, NY: Springer New York; 2013:19–27.
- Williams M. Dietary supplements and sports performance: amino acids. J Int Soc Sports Nutr. 2005;2(2):63–7.
- Ripps H, Shen W. Review: taurine: a “very essential” amino acid. Mol Vis. 2012;18(November):2673–86.
- Dawson R, Biasetti M, Messina S, Dominy J. The cytoprotective role of taurine in exercise-induced muscle injury. Amino Acids. 2002;22(4):309–24.
- Parcell S. Sulfur in human nutrition and applications in medicine. Altern Med Rev. 2002;7(1):22–44.
- Brown RP, Gerbarg PL, Ramazanov Z. Rhodiola rosea: A Phytomedicinal Overview. Herb Gram. 2002;56:40–52. Available at: http://www.powersupplements.com/rhodiola/herbalgramrhodiola.pdf.
- Kelly GS. Rhodiola rosea: A Possible Plant Adaptogen. Altern Med Rev. 2001;6(3):293–302. Available at: http://www.bio-genesis.com/productpages/eskaloft/Rhodiola Alt Med Rev 2001.pdf.
- Olsson EM, von Schéele B, Panossian AG. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue. Planta Med. 2009;75(2):105–12.
- De Bock K, Eijde BO, Ramaekers M HP. Rhodiola Rosea Can Improve Exercise Performance.pdf. 2004:298–307.
- Spasov a a, Wikman GK, Mandrikov VB, Mironova I a, Neumoin V V. A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen. Phytomedicine. 2000;7(2):85–9.
- Panossian a, Wikman G, Sarris J. Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy. Phytomedicine. 2010;17(7):481–93.
- Shevtsov VA, Zholus BI, Shervarly VI, Vol VB, Korovin YP. A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work. Phytomedicine. 2003:95–105.
- Darbinyan V, Aslanyan G, Amroyan E, Gabrielyan E, Malmström C, Panossian a. Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression. Nord J Psychiatry. 2007;61(5):343–8.
- Darbinyan V, Kteyan a, Panossian a, Gabrielian E, Wikman G, Wagner H. Rhodiola rosea in stress induced fatigue–a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty. Phytomedicine. 2000;7(5):365–71.
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